Cat Benadryl Dosage Calculator

Calculate the correct Diphenhydramine dosage in liquid milliliters (mL) or tablet ftions for feline allergies and insect stings.

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Input Parameters

Enter cat weight and formulation.

Single Recommended Dose

10.0 mg
Liquid Volume: 4.0 mL
Dosing Frequency: Every 8 to 12 Hours
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Flavoring Tip

Diphenhydramine liquid is extremely bitter to felines. Mix liquid doses into a small spoon of wet food or tuna juice to avoid intense foaming at the mouth.

Cat Benadryl Dosage Reference Chart

Cat Weight (lbs / kg) Single Dose (mg) Liquid Dose (12.5mg/5mL) 25 mg Tablet Dose
5 lbs (2.3 kg) 5.0 mg 2.0 mL 1/4 Tablet
8 lbs (3.6 kg) 8.0 mg 3.2 mL 1/3 Tablet
10 lbs (4.5 kg) 10.0 mg 4.0 mL 1/2 Tablet
12 lbs (5.4 kg) 12.0 mg 4.8 mL 1/2 Tablet
15 lbs (6.8 kg) 15.0 mg 6.0 mL 1/2 to 3/4 Tablet

Calculation Methodology & Pharmacological Guidelines

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Veterinary Dosing Formula

Dose (mg) = Body Weight (lbs) × 1.0 mg/lb Liquid Volume (mL) = (Dose mg / 12.5 mg) × 5 mL

Diphenhydramine competes with histamine for H1-receptor sites on effector cells, relieving allergic itch and inflammation.

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Veterinary Disclaimer

Never give Benadryl formulations containing decongestants or alcohol. Always verify exact dosing with your veterinarian before treatment.

Frequently Asked Questions

What is the safe Benadryl dosage for cats? ▼

The standard veterinary dosage of Benadryl (diphenhydramine) for cats is 1 mg per pound of body weight (approx 2 mg per kg), administered every 8 to 12 hours as directed by a veterinarian.

Which type of Benadryl is safe for cats? ▼

Only use plain Diphenhydramine HCl (liquid children's Benadryl 12.5 mg / 5 mL or plain 25 mg tablets). NEVER use products containing decongestants (pseudoephedrine, phenylephrine), acetaminophen, or alcohol.

What are the common side effects of Benadryl in cats? ▼

Common side effects include drowsiness, sedation, dry mouth, or paradoxically extreme agitation/hypetivity in some felines. Liquid Benadryl has a bitter taste that may cause foaming at the mouth.

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